99% Purity CAS 209216-23-9 Entecavir Monohydrate / Entecavir Hydrate

Product Details
Customization: Available
Function: Antibiotic and Antimicrobial Agents
Certification: GMP, FDA
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Number of Employees
4
Year of Establishment
2015-03-18
  • 99% Purity CAS 209216-23-9 Entecavir Monohydrate / Entecavir Hydrate
  • 99% Purity CAS 209216-23-9 Entecavir Monohydrate / Entecavir Hydrate
  • 99% Purity CAS 209216-23-9 Entecavir Monohydrate / Entecavir Hydrate
  • 99% Purity CAS 209216-23-9 Entecavir Monohydrate / Entecavir Hydrate
  • 99% Purity CAS 209216-23-9 Entecavir Monohydrate / Entecavir Hydrate
  • 99% Purity CAS 209216-23-9 Entecavir Monohydrate / Entecavir Hydrate
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Basic Info.

Model NO.
EP/USP
Grade Standard
Medicine Grade
Type
Analysis reagent
State
Solid
Volatile
Not Volatile
appearance
White Powder
Transport Package
25kg/Drum
Specification
USP/BP
Trademark
SINOAH
Origin
China
HS Code
2933990099
Production Capacity
2mt/Month

Product Description

99% Purity CAS 209216-23-9 Entecavir Monohydrate / Entecavir Hydrate 

Entecavir Hydrate is a new kind of cyclopentyl acyl guanosine anti-hepatitis b virus drugs with its pharmacological effects similar as entecavir. It is clinically applied to the treatment of adult chronic hepatitis b in which there is active viral replication, increased serum transaminase ALT or active lesions showed from liver histology. 
Entecavir Monohydrate is a kind of analogues of guanine nucleoside which has inhibitory on the polymerase of hepatitis b virus (HBV). It can become active triphosphate salts through phosphorylation. The triphosphate salt has a half-life of 15 hours inside a cell. Through completion with the natural substrates of HBV polymerase, guanine nucleoside triphosphate, entecavir triphosphate can suppress all the three types of activities of the virus polymerase (reverse transcriptase): 
(1) The initiation of HBV polymerase.
(2) The formation of the negative chain of reverse transcription of the pre-genome.
(3) The synthesis of HBVDNA positive chain.
 Product Name  Entecavir hydrate
 Synonyms

 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate

 Entecavir Monohydrate

 2-amino-9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2- methylenecyclopentyl)-1H-purin-6(9H)-one

 CAS  209216-23-9
 Molecular Formula  C12H17N5O4
 Molecular Weight  295.29
 Density  1.81g/cm3
 Melting Point  >220°C
 Boiling Point  661.4°C at 760 mmHg
 Flash Point  353.8°C
 Vapour Pressure  2.15E-18mmHg at 25°C
 Refractive Index  1.837
 Appearance  White powder
 Uses  Entecavir hydrate is an oral antiviral drug used in the treatment of hepatitis B infection. Entecavir hydrate is a nucleoside analog (more specifically, a guanine analogue) that inhibits reverse transcription, DNA replication and transcription in the vira

99% Purity CAS 209216-23-9 Entecavir Monohydrate / Entecavir Hydrate
99% Purity CAS 209216-23-9 Entecavir Monohydrate / Entecavir Hydrate99% Purity CAS 209216-23-9 Entecavir Monohydrate / Entecavir Hydrate99% Purity CAS 209216-23-9 Entecavir Monohydrate / Entecavir Hydrate99% Purity CAS 209216-23-9 Entecavir Monohydrate / Entecavir Hydrate99% Purity CAS 209216-23-9 Entecavir Monohydrate / Entecavir Hydrate99% Purity CAS 209216-23-9 Entecavir Monohydrate / Entecavir Hydrate


 

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