99% Purity CAS 209216-23-9 Entecavir Monohydrate / Entecavir Hydrate

• Function: Antibiotic and Antimicrobial Agents
• Certification: GMP, FDA
• Grade Standard: Medicine Grade
• Type: Analysis reagent
• State: Solid
• Volatile: Not Volatile
• Model NO.: EP/USP
• appearance: White Powder
• Transport Package: 25kg/Drum
• Specification: USP/BP
• Trademark: SINOAH
• Origin: China
• HS Code: 2933990099
• Production Capacity: 2mt/Month

Product Description

99% Purity CAS 209216-23-9 Entecavir Monohydrate / Entecavir Hydrate 

Entecavir Hydrate is a new kind of cyclopentyl acyl guanosine anti-hepatitis b virus drugs with its pharmacological effects similar as entecavir. It is clinically applied to the treatment of adult chronic hepatitis b in which there is active viral replication, increased serum transaminase ALT or active lesions showed from liver histology. 
Entecavir Monohydrate is a kind of analogues of guanine nucleoside which has inhibitory on the polymerase of hepatitis b virus (HBV). It can become active triphosphate salts through phosphorylation. The triphosphate salt has a half-life of 15 hours inside a cell. Through completion with the natural substrates of HBV polymerase, guanine nucleoside triphosphate, entecavir triphosphate can suppress all the three types of activities of the virus polymerase (reverse transcriptase): 
(1) The initiation of HBV polymerase.
(2) The formation of the negative chain of reverse transcription of the pre-genome.
(3) The synthesis of HBVDNA positive chain.

Product Name	Entecavir hydrate
Synonyms	2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate  Entecavir Monohydrate  2-amino-9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2- methylenecyclopentyl)-1H-purin-6(9H)-one
CAS	209216-23-9
Molecular Formula	C12H17N5O4
Molecular Weight	295.29
Density	1.81g/cm^3
Melting Point	>220°C
Boiling Point	661.4°C at 760 mmHg
Flash Point	353.8°C
Vapour Pressure	2.15E-18mmHg at 25°C
Refractive Index	1.837
Appearance	White powder
Uses	Entecavir hydrate is an oral antiviral drug used in the treatment of hepatitis B infection. Entecavir hydrate is a nucleoside analog (more specifically, a guanine analogue) that inhibits reverse transcription, DNA replication and transcription in the vira