| Function: | Antibiotic and Antimicrobial Agents |
|---|---|
| Certification: | GMP |
| Grade Standard: | Medicine Grade |
| Type: | Analysis reagent |
| State: | Solid |
| Volatile: | Not Volatile |
| Samples: |
|---|
| Customization: |
|---|
Suppliers with verified business licenses
Audited Supplier Introduction
|
Product Name: |
Thiamphenicol |
|
Synonyms : |
Methylsulfonyl chloramphenicol; thiophenicol; 2,2-dichloro-N-{1,3-dihydroxy-1-[4-(methylsulfonyl)phenyl]propan-2-yl}acetamide |
|
EINECS : |
239-355-3 |
|
Grade Standard : |
Medicine Grade |
|
Specification: |
98% |
|
Appearance: |
White fine powder |
|
Other name : |
Thiamphenine |
|
CAS.No.: |
15318-45-3 |
Specification
|
Item |
Specifications |
Results |
|
Appearance |
Fine white or yellowish-white crystalline powder or crystals |
Fine white crystalline powder |
|
Identification |
According to BP2012 |
Complies |
|
Light absorption |
According to BP2012 |
Complies |
|
Acidity or alkalinity |
According to BP2012 |
Complies |
|
m.p |
163~167ºC |
165ºC |
|
Specific optical rotation |
-21°~-24° |
-22° |
|
Chloride |
≤200ppm |
<200ppm |
|
Sulphated ash |
≤0.1% |
0.05% |
|
Heavy metals |
≤10ppm |
<10ppm |
|
Loss on drying |
≤1.0% |
0.02% |
|
Assay |
98.0%~100.5% |
99.9% |
Application
Thiamphenicol (also known as thiophenicol and dextrosulphenidol) is an antibiotic. It is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Like chloramphenicol, it is insoluble in water, but highly soluble in lipids. It is used in many countries as a veterinary antibiotic, but is available in China and Italy for use in humans. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.
Thiamphenicol is also widely used in Brazil, particularly for the treatment of sexually transmitted infections and pelvic inflammatory disease.
Unlike chloramphenicol, thiamphenicol is is not readily metabolized in cattle, poultry, sheep, or humans, but is predominantly excreted unchanged. In pigs and rats the drug is excreted both as parent drug and as thiamphenicol glucuronate
Suppliers with verified business licenses
Audited Supplier 
){kind=link}
){kind=link}