Customization: | Available |
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Function: | Antibiotic and Antimicrobial Agents |
Certification: | GMP, FDA |
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Penicillin: An antibiotic derivedfrom the mould Penicillium notatum;specifically it is known as penicillin Gand belongs to a class of similar substancescalled penicillins. They producetheir effects by disruptingsynthesis of the bacterial cell wall,and are used to treat a variety of infectionscaused by bacteria.
Melting point: |
209-212°c |
Alpha |
D24.8 +301° (c = 2.0 in water) |
Density |
1.41 |
Refractive index |
300 ° (c=2, h2o) |
Storage temp. |
2-8°c |
Solubility |
H2o: 100 mg/ml solutions should be filter sterilized and stored at 2-8°c for 1 week or at -20°c for extended periods. Solutions are stable at 37°c for 3 days. |
Form |
Powder |
Color |
Colorless or white |
PH |
5.5-7.5 (3% in h2o) |
Water solubility |
5-10 g/100 ml at 25 ºc |
Merck |
147,094 |
BRN |
3834217 |
Stability: |
Stability stable, but incompatible with a wide variety of materials, including acids, oxidizing agents, heavy metals, alcohols, glycerol, thiomersal, many surface-active agents, alkalies, peroxides, reducing agents, lanolin, glycol, sugars, amines, iodine, iodides, thiols. Hygroscopic. |
1. For the treatment of sensitive enterococci, Shigella, Salmonella, E. coli, Listeria, aerogenes, Haemophilus influenzae and Proteus mirabilis.
2. Broad-spectrum semi-synthetic penicillin drugs, low toxicity. Similar antibacterial spectrum and penicillin, penicillin-sensitive bacteria lower potency, antibacterial effect viridans with penicillin similar or slightly stronger. Against diphtheria, tetanus, and actinomycetes its effectiveness and penicillin basically the same. Enterococcus and Listeria effect is better than benzylpenicillin. And it can produce drug-resistant staph bacteria penicillin had no antibacterial effect. Effective against gram-negative bacteria, but easy to produce drug resistance.
3. Mainly caused by susceptible strains of the drug for urinary system, respiratory system, biliary tract, intestinal infections and meningitis, endocarditis.
4. Mainly used for typhoid, paratyphoid treatment; also for the urinary tract, respiratory tract infections.
Application
Sodium salt of Penicillin G, an antibacterial, antimicrobial medication. Used in the treatment of pneumococcus and streptococcus bacterial infections.