99% High Quality Pharmaceutical Material Esomeprazole Sodium CAS 161796-78-7

• Function: Antibiotic and Antimicrobial Agents
• Certification: GMP
• Grade Standard: Medicine Grade
• Type: Analysis reagent
• State: Solid
• Volatile: Not Volatile
• Model NO.: USP
• appearance: Almost White Powder
• Assay: 99.8%
• Transport Package: 25kg/Drum
• Specification: USP/BP
• Trademark: SINOAH
• Origin: China
• HS Code: 3003101200
• Production Capacity: 5mt/Month

Product Description

SINOAH 99% High Quality Pharmaceutical Material Esomeprazole Sodium CAS 161796-78-7
 

Introduction 

Name		Esomeprazole sodium
Synonyms		5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl-1H-benzimidazole sodium salt
Molecular Structure
Molecular Formula		C17H20N3NaO3S
Molecular Weight		369.41
CAS Registry Number		161796-78-7

Esomeprazole is in a group of drugs called proton pump inhibitors. Esomeprazole decreases the amount of acid produced in the stomach.

Esomeprazole is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Esomeprazole is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).

Function

Esomeprazole sodium is used in the treatment of dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome.

Specification

Test items	Specifications	Result
Appearance	White or slightly coloured powder,slight hygroscopic	almost white powder
Identification A. IR B.Enantiomeric purity C.Reaction of maganesium D. Water	IR Conforms to the CRS.(2.2.24) Impurity F  ≤0.2%(2.2.29) It gives reaction of magnesium(2.3.1) 6.2%~8.0%(2.5.12)	Complies 0.05% Complies 7.3%
Absorbance	The absorbance is not greater than 0.20 at 440nm.(2.2.25)	0.12
Related substances(HPLC) Impurity E Impurity D Unspecified  impurities Total impurity  Impurity F	(2.2.29) ≤0.15% ≤0.15% ≤0.10% ≤0.3% ≤0.2%(2.2.29)	0.04% 0.10% 0.03% 0.2% 0.05%
Magnesium	3.30%~3.55%	3.46%
Water by K.F.	6.2%~8.0%(2.5.12)	7.3%
Assay(HPLC)	98.0%~102.0%(2.2.29)	99.9%
Residual solvents: a) Acetone b)Ethyl acetate c)Methylene chloride d)Methanol e)Toluene f)Benzene	Not more than 5000ppm Not more than 5000ppm Not more than 100ppm Not more than 3000ppm Not more than 890ppm Not more than 2ppm	3ppm Not detected Not detected 77ppm Not detected Not detected