| Customization: | Available |
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| Function: | Antibiotic and Antimicrobial Agents |
| Certification: | GMP |
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Basic information
CAS No:115550-35-1
MF: C17H19FN4O4 Einecs No.:N/a
Appearance:Light yellow powder Grade Standard:Medicine Grade
Usage:Animal Pharmaceuticals Shelf Life:2 Year
MARBOFLOXACIN CAS 115550-35-1
Property: Light Yellow Crystalline Powder,New type of animal dedicated fluoroquinolone drugs. Marbofloxacin is a new type of fluoroquinolone antibiotic, by inhibiting bacterial DNA transcription to inhibit the growth of bacteria, the gram-negative bacteria, gram-positive bacteria and mycoplasma have antibacterial activity. Ma Bo effect through oral and injected drugs were able to absorb good, low toxic and side effect.
Pharmacokinetics: absorption was rapid and complete after administration and injection, plasma protein binding rate was low, tissue distribution was wide, and it was well distributed in kidney, liver, lung and skin. The oral bioavailability of pregnant sows and cats was about 80%, and that of calves was more than 100%. All the tissue concentrations detected were higher than those in plasma. Some of them were metabolized into inactive metabolites such as N-demethylation MBF and N-oxygen MBF in the liver. The main excretion pathway was the kidney, and the canine excreted 3045% of the prototype drug in urine. Intramuscular injection and subcutaneous administration of fowl (intramuscular injection), broiler (intramuscular injection), sows (intramuscular injection) were 4.33, 5.265.74 and 10 h, respectively, and the effective blood concentration was maintained for a longer period of time after intramuscular injection and subcutaneous injection, respectively, for 14 h and 13 h.
Application: Fluoroquinolone antibiotic, used for treatment of deep and superficial skin infection, urinary tract infection, the cat's skin and soft tissue infection, acute upper respiratory tract infection. Used for sensitive bacteria caused by cattle, pigs, dogs, cats, respiratory tract, the digestive tract, urinary tract, skin infections, etc. For cattle, sheep mastitis mastitis and pigs - metritis - no milk syndrome are malignant.
Use:Used for sensitive bacteria caused by cattle, pigs, dogs, cats, respiratory tract, the digestive tract, urinary tract, skin infections, etc. For cattle, sheep mastitis mastitis and pigs - metritis - no milk syndrome are malignant.
Specification:
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(ITEMS ) |
( STANDARDS ) |
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Appearance |
Light yellowish Crystalline powder |
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Solubility |
Water |
Slightly soluble |
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Sparingly soluble |
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Ethanol (96%) |
Very slightly soluble |
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Identification -IR Spectrum |
Concordant with the spectrum of reference substance |
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Absorbance |
≤0.20 |
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Related substances (%) |
Impurity C, D, E |
≤0.2% |
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Impurity A, B |
≤0.1% |
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Unspecified Impurities |
≤0.2% |
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Total Impurity |
≤0.5% |
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Heavy metal |
≤20ppm |
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Loss on drying |
≤0.5% |
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Sulphated ash |
≤0.10% |
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Assay(on the dried basis): |
99.0%-101.0% |
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